Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.59 |
| ▸ | ABAT | P80404 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | IGF2R | P11717 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 2/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.53 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508495 | 1.00 | EGFR (0.68) | EGFRALDH1A1TRIM24HPGDALDH5A1 | |
| SCHEMBL11549693 | 0.88 | CYP1A2 (0.62) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL11549689 | 0.88 | CYP1A2 (0.62) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL9124369 | 0.83 | EGFR (0.58) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL9124372 | 0.83 | EGFR (0.58) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL8743696 | 0.81 | EGFR (1.00) | EGFRALDH1A1TRIM24HPGDALDH5A1 | |
| SCHEMBL10280982 | 0.80 | EGFR (0.45) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL11549421 | 0.80 | NQO1 (0.54) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL11549417 | 0.80 | NQO1 (0.54) | EGFRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL6331872 | 0.80 | ALDH1A1 (0.69) | EGFRALDH1A1TRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |
| EP-0555465-A1 | RADIOGRAPHIC ELEMENT | EASTMAN KODAK COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1993005444-A1 | RADIOGRAPHIC ELEMENT | EASTMAN KODAK COMPANY (US) | 1993-03-18 | — | — | WO | disclosed |