Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868923 | 0.84 | SLC6A4 (0.50) | AKR1C1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL869351 | 0.81 | DPP4 (0.50) | AKR1C1HDAC4GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL11188094 | 0.77 | OPRM1 (0.51) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL11188090 | 0.77 | OPRM1 (0.51) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL19265008 | 0.75 | AKR1C1 (0.42) | AKR1C1HDAC4SLC6A2SLC6A3DPP4 | |
| SCHEMBL1040024 | 0.75 | OPRL1 (0.55) | AKR1C1HDAC4OPRM1OPRD1 | |
| SCHEMBL29195226 | 0.75 | OPRL1 (0.55) | AKR1C1HDAC4OPRM1OPRD1 | |
| SCHEMBL60129 | 0.75 | OPRL1 (0.55) | AKR1C1HDAC4OPRM1OPRD1 | |
| SCHEMBL4556223 | 0.75 | OPRL1 (0.55) | AKR1C1HDAC4OPRM1OPRD1 | |
| SCHEMBL16469256 | 0.75 | OPRL1 (0.55) | AKR1C1HDAC4OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351846-B1 | Phenylbicyclohexanol ester derivative | DAINIPPON INK & CHEMICALS (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0351846-A3 | PHENYLBICYCLOHEXANOL ESTER DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0351846-A2 | Phenylbicyclohexanol ester derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-01-24 | — | — | EP | disclosed |