Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512375 | 0.95 | S1PR1 (0.48) | ACACBS1PR1S1PR3LMNARARB | |
| SCHEMBL9509310 | 0.93 | RARB (0.48) | ACACBS1PR1S1PR3LMNAL3MBTL1 | |
| SCHEMBL9512415 | 0.93 | ACACB (0.46) | ACACBS1PR1S1PR3C3AR1LMNA | |
| SCHEMBL9508714 | 0.92 | RARB (0.50) | ACACBS1PR1S1PR3C3AR1LMNA | |
| SCHEMBL9509225 | 0.91 | ACACB (0.43) | ACACBS1PR1S1PR3MCHR1 | |
| SCHEMBL9509028 | 0.91 | ACACB (0.45) | ACACBS1PR1S1PR3L3MBTL1RARB | |
| SCHEMBL9512246 | 0.91 | RARB (0.52) | ACACBS1PR1S1PR3C3AR1LMNA | |
| SCHEMBL9510037 | 0.91 | RARB (0.52) | ACACBS1PR1S1PR3C3AR1LMNA | |
| SCHEMBL9509214 | 0.90 | S1PR1 (0.48) | ACACBS1PR1S1PR3LMNARARB | |
| SCHEMBL10511036 | 0.89 | RARB (0.47) | ACACBS1PR1S1PR3C3AR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |