Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141103 | 1.00 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1BACE1TSHRALDH1A1 | |
| SCHEMBL9508803 | 1.00 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1BACE1TSHRALDH1A1 | |
| SCHEMBL879908 | 0.94 | BACE1 (0.51) | CYSLTR2CYSLTR1BACE1TSHRALDH1A1 | |
| SCHEMBL10900181 | 0.88 | BACE1 (0.53) | BACE1TSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL10900178 | 0.88 | BACE1 (0.53) | BACE1TSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL9305141 | 0.86 | TSHR (0.49) | BACE1TSHRALDH1A1LMNASOAT2 | |
| SCHEMBL9504870 | 0.84 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1ALDH1A1SOAT2SOAT1 | |
| SCHEMBL22439056 | 0.84 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1ALDH1A1SOAT2SOAT1 | |
| SCHEMBL22439053 | 0.84 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1ALDH1A1SOAT2SOAT1 | |
| SCHEMBL14672873 | 0.84 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1ALDH1A1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |