Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623545 | 0.99 | MEN1 (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9623550 | 0.99 | MEN1 (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL4609127 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6754408 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL4610015 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6754133 | 0.79 | ALDH1A1 (0.51) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6754130 | 0.79 | ALDH1A1 (0.51) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1352270 | 0.77 | ALDH1A1 (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL4657892 | 0.77 | ALDH1A1 (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9191113 | 0.76 | MAPT (0.56) | MAPTALDH1A1TSHRLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232972-B1 | NEGATIVE PHOTORESIST COMPOSITIONS AND PROCESSES FOR PREPARING THERMALLY STABLE, NEGATIVE IMAGES USING THEM | ROHM AND HAAS COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0232972-A2 | Negative photoresist compositions and processes for preparing thermally stable, negative images using them | ROHM AND HAAS COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |