Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511467 | 0.96 | RARB (0.51) | RARBCASP3SENP8SENP7SENP6 | |
| SCHEMBL9510020 | 0.95 | RARB (0.53) | RARBCASP3SENP8SENP7SENP6 | |
| SCHEMBL9508915 | 0.95 | RARB (0.53) | RARBCASP3SENP8SENP7SENP6 | |
| SCHEMBL9511326 | 0.93 | MAOB (0.43) | RARBMAOBS1PR1S1PR3FFAR1 | |
| SCHEMBL10513151 | 0.92 | RARB (0.47) | RARBCASP3SENP8SENP7SENP6 | |
| SCHEMBL9509214 | 0.91 | S1PR1 (0.48) | RARBS1PR1S1PR3FFAR1LMNA | |
| SCHEMBL9509387 | 0.90 | RARB (0.46) | RARBS1PR1S1PR3FFAR1LMNA | |
| SCHEMBL9512415 | 0.89 | ACACB (0.46) | RARBS1PR1S1PR3FFAR1LMNA | |
| SCHEMBL9512354 | 0.89 | RARB (0.51) | RARBS1PR1S1PR3LMNAMEN1 | |
| SCHEMBL9512515 | 0.88 | RARB (0.52) | RARBCASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |