Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508924 | 0.93 | RARB (0.46) | MAOBAPPCYP2C19FFAR1MCHR1 | |
| SCHEMBL9511467 | 0.91 | RARB (0.51) | MAOBAPPCYP2C19FFAR1MCHR1 | |
| SCHEMBL9508915 | 0.90 | RARB (0.53) | MAOBAPPCYP2C19FFAR1RARB | |
| SCHEMBL9510020 | 0.90 | RARB (0.53) | MAOBAPPCYP2C19FFAR1RARB | |
| SCHEMBL9509028 | 0.90 | ACACB (0.45) | FFAR1RARBS1PR1S1PR3 | |
| SCHEMBL9512526 | 0.90 | APP (0.43) | MAOBAPPCYP2C19FFAR1MCHR1 | |
| SCHEMBL10513151 | 0.89 | RARB (0.47) | MAOBAPPCYP2C19FFAR1RARB | |
| SCHEMBL9508758 | 0.89 | ACACB (0.48) | MCHR1RARBS1PR1S1PR3 | |
| SCHEMBL9512375 | 0.89 | S1PR1 (0.48) | CYP2C19FFAR1MCHR1RARBS1PR1 | |
| SCHEMBL9509310 | 0.86 | RARB (0.48) | RARBS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |