SCHEMBL9508943

SCHEMBL9508943

Clc1nc(C(Cl)Cl)ns1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8803498 0.80
SCHEMBL14262249 0.75
SCHEMBL8809450 0.71
SCHEMBL81344 0.65 NPC1 (0.33)
SCHEMBL697284 0.65
SCHEMBL2079340 0.61
SCHEMBL14291320 0.61
SCHEMBL547688 0.61
SCHEMBL21915884 0.61
SCHEMBL14262471 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348737-B1 HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES BAYER AG (DE) 1993-08-04 EP disclosed
US-5090991-A HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES BAYER AKATIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4968342-A PRE-AND POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0348737-A1 Heteroaryloxy-acetic acid N-isopropyl anilides BAYER AG (DE) 1990-01-03 EP disclosed
EP-0192180-B1 5-(AZOLYLOXYPHENYLCARBAMOYL)-BARBITURIC ACID DERIVATIVES AS ACTIVE AGENTS IN ANTHELMICS CIBA-GEIGY AG (CH) 1989-08-09 EP disclosed
US-4762830-A 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics CIBA-GEIGY CORPORATION (US) 1988-08-09 US disclosed
EP-0192180-A1 5-(Azolyloxyphenylcarbamoyl)-barbituric acid derivatives as active agents in anthelmics CIBA-GEIGY AG (CH) 1986-08-27 EP disclosed