Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.51 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504997 | 0.88 | KLK5 (0.55) | ACEATMAPPPSEN1PSEN2 | |
| SCHEMBL7324443 | 0.88 | ACE (0.67) | ACEATMAPPPSEN1PSEN2 | |
| SCHEMBL9508990 | 0.82 | ATM (0.50) | ACEATMAPPPSEN1PSEN2 | |
| SCHEMBL835353 | 0.81 | ATM (0.53) | ACEATMCTSSCTSLCTSB | |
| SCHEMBL14738131 | 0.81 | ATM (0.53) | ACEATMCTSSCTSLCTSB | |
| SCHEMBL1991941 | 0.81 | ATM (0.53) | ACEATMCTSSCTSLCTSB | |
| SCHEMBL1790255 | 0.81 | ACE (0.65) | ACEATMAPPPSEN1PSEN2 | |
| SCHEMBL20836770 | 0.80 | NAALAD2 (0.66) | ACEATMAPPCTSSCTSL | |
| SCHEMBL1323164 | 0.80 | NAALAD2 (0.66) | ACEATMAPPCTSSCTSL | |
| SCHEMBL9439238 | 0.80 | NAALAD2 (0.66) | ACEATMAPPCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556405-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | Japan Tobacco Inc. (JP) | 1993-08-25 | — | — | EP | disclosed |
| WO-1993004080-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1993-03-04 | — | — | WO | disclosed |