Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.53 |
| ▸ | FAP | Q12884 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29541867 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6092096 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8862702 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6933624 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| Bromide SCHEMBL7274107 | 0.86 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL6348160 | 0.86 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30051426 | 0.85 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9508348 | 0.84 | ACE (0.59) | OPRM1ACE | |
| Trifluoroacetic Acid SCHEMBL9551620 | 0.82 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9509127 | 0.79 | ACE (0.63) | DPP4ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316218-B1 | L-PROLINE DERIVATIVES, THEIR PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | EKITA Investments N.V. (NA) | 1993-09-15 | — | — | EP | disclosed |
| EP-0316218-A1 | L-proline derivatives, their preparation and biological applications thereof | EKITA Investments N.V. (NA) | 1989-05-17 | — | — | EP | disclosed |