Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773048 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4652946 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4652947 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4653934 | 0.82 | ALDH1A1 (0.56) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6398636 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6398640 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5272951 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL111577 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL10791380 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4652939 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559656-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009592-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-06-11 | — | — | WO | disclosed |