Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KLK8 | O60259 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | KLK2 | P20151 | 2/20 | 0.46 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13541272 | 0.88 | TSHR (0.49) | L3MBTL1ALDH1A1 | |
| SCHEMBL13538269 | 0.87 | TSHR (0.47) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL1822019 | 0.87 | SRC (0.56) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL11145964 | 0.86 | L3MBTL1 (0.52) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL2595713 | 0.85 | SRC (0.54) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL8370393 | 0.83 | SRC (0.52) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL11146084 | 0.81 | SRC (0.50) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL11124425 | 0.81 | SRC (0.50) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL20813386 | 0.79 | SRC (0.48) | SRCL3MBTL1TDP1KLK8PLAU | |
| Hydrochloric Acid SCHEMBL7526008 | 0.79 | SRC (0.48) | SRCL3MBTL1TDP1KLK8PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300542-B1 | THERMALLY STABLE DIPHOSPHONATE-TYPE FLAME RETARDANT ADDITIVE FOR PLASTICS | Akzo Nobel N.V. (NL) | 1993-09-29 | — | — | EP | claimed |
| US-4910240-A | Containing a diphosphonate | AKZO AMERICA INC. (US) | 1990-03-20 | — | — | US | claimed |
| EP-0300542-A1 | Thermally stable diphosphonate-type flame retardant additive for plastics | Akzo Nobel N.V. (NL) | 1989-01-25 | — | — | EP | claimed |
| EP-0300542-B1 | THERMALLY STABLE DIPHOSPHONATE-TYPE FLAME RETARDANT ADDITIVE FOR PLASTICS | Akzo Nobel N.V. (NL) | 1993-09-29 | — | — | EP | disclosed |
| US-4910240-A | Containing a diphosphonate | AKZO AMERICA INC. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0300542-A1 | Thermally stable diphosphonate-type flame retardant additive for plastics | Akzo Nobel N.V. (NL) | 1989-01-25 | — | — | EP | disclosed |