Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.33 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513089 | 0.94 | CYP1A2 (0.40) | TSHRSMN1; SMN2ALDH1A1CYP1A2MAPT | |
| SCHEMBL9511781 | 0.94 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9512536 | 0.89 | MAPT (0.39) | TSHRSMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL9514426 | 0.77 | MAPT (0.39) | SMN1; SMN2ALDH1A1LMNACYP1A2MAPT | |
| SCHEMBL11203598 | 0.76 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL5792011 | 0.76 | GAA (0.52) | TSHRALDH1A1CYP1A2MAPT | |
| SCHEMBL10917864 | 0.71 | MAPT (0.35) | TSHRSMN1; SMN2ALDH1A1CYP1A2MAPT | |
| SCHEMBL3642355 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNACYP1A2MAPT | |
| SCHEMBL10945264 | 0.69 | KDM4E (0.47) | TSHRSMN1; SMN2ALDH1A1MAPTCASR | |
| SCHEMBL10922123 | 0.69 | KDM4E (0.33) | TSHRSMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256626-A | Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds | MONSANTO COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0565593-A1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO COMPANY (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0562015-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |