Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 17/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741980 | 0.84 | SLC2A1 (0.48) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764490 | 0.82 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764465 | 0.82 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9742764 | 0.80 | SLC2A1 (0.49) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL9021318 | 0.79 | ADRB2 (0.61) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9509569 | 0.79 | SLC2A1 (0.52) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764380 | 0.78 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| Picumeterol SCHEMBL9857897 | 0.78 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| Picumeterol SCHEMBL156907 | 0.78 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| Picumeterol SCHEMBL83175 | 0.78 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-B1 | ETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-22 | — | — | EP | disclosed |
| US-5039697-A | Adrenergic stimulants, bronchodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5032609-A | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| US-5002966-A | Adrenergic Stimulants | GLAXO GROUP LIMITED (GB) | 1991-03-26 | — | — | US | disclosed |