Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 4/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513032 | 0.88 | KDM4E (0.47) | TOP1TOP2ATOP2BKDM4EHPGD | |
| SCHEMBL9512987 | 0.87 | STAT3 (0.39) | TOP1STAT3CNR1CNR2KDM4E | |
| SCHEMBL9560364 | 0.86 | TOP1 (0.38) | TOP1STAT3CNR1CNR2TOP2A | |
| SCHEMBL9509708 | 0.85 | TOP1 (0.52) | TOP1TOP2ATOP2BKDM4EKMT2A | |
| SCHEMBL9509563 | 0.84 | TOP1 (0.40) | TOP1STAT3TOP2ATOP2BKDM4E | |
| SCHEMBL9512154 | 0.83 | KDM4E (0.50) | TOP1TOP2ATOP2BKDM4EHPGD | |
| SCHEMBL9569195 | 0.83 | TOP1 (0.40) | TOP1CNR1CNR2TOP2ATOP2B | |
| SCHEMBL9560601 | 0.81 | TOP1 (0.45) | TOP1STAT3CNR1CNR2TOP2A | |
| SCHEMBL10543498 | 0.80 | STAT3 (0.52) | TOP1STAT3CNR1CNR2KDM4E | |
| SCHEMBL9560540 | 0.80 | TOP1 (0.36) | TOP1KDM4EKMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | claimed |
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |