Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560538 | 0.90 | TOP1 (0.45) | TOP1ALDH1A1KDM4EGAAGPR35 | |
| SCHEMBL9560529 | 0.89 | ALDH1A1 (0.38) | FPR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9509563 | 0.87 | TOP1 (0.40) | TOP1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9509713 | 0.80 | TOP1 (0.40) | TOP1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9510131 | 0.78 | TOP1 (0.36) | TOP1KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL9560364 | 0.77 | TOP1 (0.38) | TOP1 | |
| SCHEMBL9569195 | 0.75 | TOP1 (0.40) | TOP1ALDH1A1KDM4E | |
| SCHEMBL9569192 | 0.74 | TOP1 (0.37) | TOP1CYP3A4 | |
| SCHEMBL9560110 | 0.74 | SMN1; SMN2 (0.36) | TOP1FPR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9509558 | 0.74 | TOP1 (0.52) | TOP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |