SCHEMBL9509748

SCHEMBL9509748

CCCCC=CCC(F)(C(=O)O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 2/20 0.46
F3 P13726 2/20 0.46
FAAH O00519 5/20 0.45
CES1 P23141 2/20 0.45
MAPT P10636 3/20 0.42
BLM P54132 3/20 0.42
PLA2G4A P47712 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PLA2G4B P0C869 1/20 0.42
MGLL Q99685 1/20 0.42
PLA2G4C Q9UP65 1/20 0.42
GGPS1 O95749 1/20 0.42
PPARG P37231 4/20 0.42
TERT O14746 3/20 0.42
PTPN1 P18031 3/20 0.42
PPARD Q03181 3/20 0.42
PPARA Q07869 3/20 0.42
TOP1 P11387 3/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509746 1.00 F7 (0.46) F7F3FAAHCES1MAPT
SCHEMBL9508974 0.95 FAAH (0.51) F7F3FAAHCES1MAPT
SCHEMBL9508982 0.95 FAAH (0.51) F7F3FAAHCES1MAPT
SCHEMBL9509794 0.95 FAAH (0.51) F7F3FAAHCES1MAPT
SCHEMBL9509792 0.95 FAAH (0.51) F7F3FAAHCES1MAPT
SCHEMBL9509757 0.93 FAAH (0.54) F7F3FAAHCES1MAPT
SCHEMBL9508952 0.93 FAAH (0.54) F7F3FAAHCES1MAPT
SCHEMBL9509752 0.93 FAAH (0.54) F7F3FAAHCES1MAPT
SCHEMBL9508957 0.93 FAAH (0.54) F7F3FAAHCES1MAPT
SCHEMBL9509784 0.89 FAAH (0.36) F7F3FAAHCES1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350334-B1 A process for producing fluorine-containing compounds NIPPON MINING CO (JP) 1993-10-27 EP disclosed
US-5126482-A Process for producing fluorine-containing carboxylic acids NIPPON MINING CO., LTD. (JP) 1992-06-30 US disclosed