Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511121 | 1.00 | LMNA (0.62) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL9511067 | 1.00 | LMNA (0.62) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL9507403 | 0.98 | LMNA (0.59) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL9508692 | 0.93 | LMNA (0.52) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL27465616 | 0.93 | LMNA (0.71) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL365376 | 0.87 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL9768561 | 0.87 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL22223951 | 0.87 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL8419699 | 0.87 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL18187969 | 0.87 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |