Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11911283 | 0.84 | RARB (0.50) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL10491346 | 0.82 | NR5A1 (0.43) | RARBNR5A1CYP3A4CYP2D6TP53 | |
| SCHEMBL10491344 | 0.82 | NR5A1 (0.43) | RARBNR5A1CYP3A4CYP2D6TP53 | |
| SCHEMBL9333683 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330971 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330690 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330676 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9333696 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330957 | 0.82 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9509812 | 0.82 | KDM4E (0.45) | RARBNR5A1CYP3A4CYP2D6SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |