Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839323 | 0.91 | L3MBTL1 (0.48) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9840404 | 0.91 | L3MBTL1 (0.48) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9512654 | 0.84 | L3MBTL1 (0.44) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9512008 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9514935 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9515878 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9514505 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9514957 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9509914 | 0.82 | RARB (0.49) | KDM4EL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL9237686 | 0.81 | L3MBTL1 (0.43) | KDM4EL3MBTL1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |