SCHEMBL9509918

SCHEMBL9509918

CCCc1ccc(C(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.53
MCL1 Q07820 1/20 0.51
PTPN1 P18031 2/20 0.50
FOLH1 Q04609 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN6 P29350 1/20 0.50
LTB4R2 Q9NPC1 5/20 0.49
PPARG P37231 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
PPARA Q07869 1/20 0.48
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
BRS3 P32247 1/20 0.46
SORT1 Q99523 1/20 0.46
AGTR1 P30556 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28008439 0.91 PPARA (0.56) METAP2LTB4R2PPARGPPARABRS3
SCHEMBL18038416 0.88 PPARA (0.65) LTB4R2PPARGPPARA
SCHEMBL3744651 0.87 FOLH1 (0.67) METAP2MCL1PTPN1FOLH1PTPN2
SCHEMBL10909137 0.87 PTPN1 (0.53) METAP2PTPN1FOLH1PTPN2PTPN6
SCHEMBL9842588 0.85 RARB (0.63) MCL1PPARGPPARA
SCHEMBL28560553 0.85 LTB4R2 (0.50) METAP2PTPN1LTB4R2HDAC7CNR1
SCHEMBL29100387 0.84 BACE1 (0.64) PTPN1FOLH1PTPN2PTPN6HDAC7
SCHEMBL9755592 0.84 RARB (0.65) MCL1PPARGPPARA
SCHEMBL6775461 0.83 PTPN1 (0.56) PTPN1FOLH1PTPN2PTPN6LTB4R2
SCHEMBL7512343 0.83 LTB4R2 (0.53) METAP2MCL1LTB4R2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3367143-B1 POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME TRANSITIONS OPTICAL INC (US) 2023-01-11 EP claimed
EP-1639058-B1 PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2020-10-21 EP claimed
EP-0279630-B1 DEVELOPER FOR LIGHT-SENSITIVE LITHOGRAPHIC PRINTING PLATE CAPABLE OF PROCESSING COMMONLY THE NEGATIVE-TYPE AND THE POSITIVE TYPE AND DEVELOPER COMPOSITION FOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1993-10-13 EP claimed
EP-0279630-A1 Developer for light-sensitive lithographic printing plate capable of processing commonly the negative-type and the positive type and developer composition for light-sensitive material KONICA CORPORATION (JP) 1988-08-24 EP claimed
CN-104540855-A Catalyst components for the polymerization of olefins BASELL POLIOLEFINE SPA 2015-04-22 CN disclosed
EP-0279630-B1 DEVELOPER FOR LIGHT-SENSITIVE LITHOGRAPHIC PRINTING PLATE CAPABLE OF PROCESSING COMMONLY THE NEGATIVE-TYPE AND THE POSITIVE TYPE AND DEVELOPER COMPOSITION FOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1993-10-13 EP disclosed
US-5106724-A High speed, odorless KONICA CORPORATION (JP) 1992-04-21 US disclosed
EP-0279630-A1 Developer for light-sensitive lithographic printing plate capable of processing commonly the negative-type and the positive type and developer composition for light-sensitive material KONICA CORPORATION (JP) 1988-08-24 EP disclosed