SCHEMBL10909137

SCHEMBL10909137

CCc1ccc(C(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.53
FOLH1 Q04609 2/20 0.53
PTPN2 P17706 1/20 0.53
PTPN6 P29350 1/20 0.53
METAP2 P50579 1/20 0.51
HDAC7 Q8WUI4 2/20 0.51
BCL2 P10415 1/20 0.49
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 2/20 0.47
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LTB4R2 Q9NPC1 4/20 0.46
PLA2G2A P14555 3/20 0.46
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20594609 0.91 RAB9A (0.54) FOLH1METAP2HDAC7BCL2RAB9A
SCHEMBL9509918 0.87 METAP2 (0.53) PTPN1FOLH1PTPN2PTPN6METAP2
SCHEMBL3737187 0.86 FOLH1 (0.71) PTPN1FOLH1PTPN2PTPN6METAP2
SCHEMBL6775461 0.86 PTPN1 (0.56) PTPN1FOLH1PTPN2PTPN6HDAC7
SCHEMBL28565657 0.85 GABRA1 (0.49) METAP2HDAC7RAB9ASMN1; SMN2LMNA
SCHEMBL20178622 0.85 KMO (0.47) RAB9ASMN1; SMN2LMNAALDH1A1NPC1
SCHEMBL28008439 0.84 PPARA (0.56) METAP2LTB4R2
SCHEMBL6679972 0.83 PTPN1 (0.53) PTPN1FOLH1PTPN2PTPN6HDAC7
SCHEMBL6777102 0.83 PTPN1 (0.53) PTPN1FOLH1PTPN2PTPN6HDAC7
SCHEMBL27650066 0.83 CSNK2A1 (0.53) PTPN1FOLH1PTPN2PTPN6HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101001887-B Multi-branched polymer and method for producing same NIPPON SODA CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101593852-B Multibranched polymers and process for production thereof NIPPON SODA CO 2011-03-02 CN disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 CN disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 CN disclosed
US-4624532-A IMPROVED COLOR FOR ELECTRO-OPTICAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1986-11-25 US disclosed
US-4356102-A Dichroic liquid crystal compositions containing anthraquinone-based dyes GENERAL ELECTRIC COMPANY (US) 1982-10-26 US disclosed