Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 6/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510169 | 0.96 | TSHR (0.46) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9510003 | 0.96 | TSHR (0.43) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9508736 | 0.93 | HSD17B10 (0.48) | TSHRHSD17B10MPLRARBALDH1A1 | |
| SCHEMBL9510034 | 0.93 | TSHR (0.41) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9508728 | 0.93 | HSD17B10 (0.48) | TSHRHSD17B10MPLRARBALDH1A1 | |
| SCHEMBL9508790 | 0.93 | TSHR (0.41) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9510180 | 0.92 | TSHR (0.40) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9511464 | 0.92 | TSHR (0.40) | FFAR1TSHRHSD17B10MPLRARB | |
| SCHEMBL9512281 | 0.92 | FFAR1 (0.42) | FFAR1TSHRHSD17B10MPLALDH1A1 | |
| SCHEMBL9512420 | 0.92 | HSD17B10 (0.49) | TSHRHSD17B10MPLRARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |