Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 9/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509936 | 0.96 | FFAR1 (0.40) | TSHRHSD17B10RARBFFAR1HSD11B1 | |
| SCHEMBL9512420 | 0.96 | HSD17B10 (0.49) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508728 | 0.95 | HSD17B10 (0.48) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508736 | 0.95 | HSD17B10 (0.48) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508767 | 0.94 | HSD17B10 (0.47) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9512329 | 0.94 | HSD17B10 (0.47) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508830 | 0.92 | HSD17B10 (0.46) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9512306 | 0.92 | HSD17B10 (0.46) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9510003 | 0.92 | TSHR (0.43) | TSHRHSD17B10RARBFFAR1HSD11B1 | |
| SCHEMBL9512364 | 0.91 | TSHR (0.45) | TSHRHSD17B10RARBFFAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |