Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | HRH2 | P25021 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433646 | 0.96 | RAB9A (0.47) | HRH3RAB9AACACBMAOAMAOB | |
| SCHEMBL9511375 | 0.96 | RAB9A (0.47) | HRH3RAB9AACACBMAOAMAOB | |
| SCHEMBL9510023 | 0.95 | RAB9A (0.50) | HRH3HRH2HRH1RAB9AMCHR1 | |
| SCHEMBL11287806 | 0.93 | RAB9A (0.49) | HRH3HRH2HRH1RAB9AACACB | |
| SCHEMBL9510177 | 0.92 | RAB9A (0.48) | HRH3HRH2HRH1RAB9AMCHR1 | |
| SCHEMBL9511312 | 0.90 | RAB9A (0.53) | HRH3RAB9AACACBMAOAMAOB | |
| SCHEMBL9512520 | 0.89 | ESR2 (0.42) | HRH3HRH2HRH1MCHR1CHRM1 | |
| SCHEMBL18464120 | 0.89 | RAB9A (0.52) | HRH3RAB9AMAOAMAOBMAPT | |
| SCHEMBL9510031 | 0.88 | ACACB (0.44) | HRH3HRH2HRH1RAB9AMCHR1 | |
| SCHEMBL10510825 | 0.88 | MCHR1 (0.45) | HRH3HRH2HRH1RAB9AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |