Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12847415 | 0.69 | APOBEC3G (0.71) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL1543721 | 0.67 | KDM4E (0.67) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL8888876 | 0.65 | KDM4E (0.50) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL8527189 | 0.65 | KDM4E (0.50) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL6621860 | 0.65 | KDM4E (0.50) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL1544262 | 0.64 | KDM4E (0.62) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL1544148 | 0.63 | APOBEC3G (0.61) | TDP1CYP1A2KDM4EAPOBEC3GGAA | |
| SCHEMBL9511179 | 0.63 | SMN1; SMN2 (0.38) | CYP1A2KDM4EGAAALDH1A1MAPT | |
| SCHEMBL9488720 | 0.62 | KDM4E (0.51) | TDP1KDM4EAPOBEC3GGAAALDH1A1 | |
| SCHEMBL8978645 | 0.62 | KDM4E (0.71) | TDP1CYP1A2KDM4EAPOBEC3GGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398096-B1 | SUBSTITUTED TRIAZOLONES | BAYER AG (DE) | 1993-10-13 | — | — | EP | claimed |