Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529960 | 0.77 | KDM4E (0.37) | KDM4EAPOBEC3GGAACYP1A2MEN1 | |
| SCHEMBL6643747 | 0.74 | LMNA (0.40) | KDM4EAPOBEC3GGAATDP1ALDH1A1 | |
| SCHEMBL8978649 | 0.71 | ALDH1A1 (0.78) | KDM4EAPOBEC3GTDP1CYP1A2MEN1 | |
| SCHEMBL12847415 | 0.69 | APOBEC3G (0.71) | KDM4EAPOBEC3GGAATDP1CYP1A2 | |
| SCHEMBL14266674 | 0.69 | TTR (0.33) | KDM4EGAATDP1MEN1KMT2A | |
| SCHEMBL1543721 | 0.67 | KDM4E (0.67) | KDM4EAPOBEC3GGAATDP1CYP1A2 | |
| SCHEMBL14256477 | 0.66 | TTR (0.32) | KDM4EGAATDP1CYP1A2ALDH1A1 | |
| SCHEMBL9510041 | 0.65 | TDP1 (0.51) | KDM4EAPOBEC3GGAATDP1CYP1A2 | |
| SCHEMBL6621860 | 0.65 | KDM4E (0.50) | KDM4EAPOBEC3GGAATDP1CYP1A2 | |
| SCHEMBL8888876 | 0.65 | KDM4E (0.50) | KDM4EAPOBEC3GGAATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739349-A | CHEMICAL INTERMEDIATE FOR HERBICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0661277-B1 | Process for making triazolines and new untermediates used therein | BAYER AG (DE) | 1998-03-11 | — | — | EP | disclosed |
| US-5688963-A | CHEMICAL INTERMEDIATES FOR PREPARATION OF HERBICIDES AND INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| EP-0657437-B1 | Process and novel intermediates for the preparation of triazolinones | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5639891-A | HERBICIDES; INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | disclosed |
| US-5508420-A | REACTING TRIAZOLINETHIONE WITH OXIDANT, REACTING FORMED TRIAZOLESULFONIC ACID WITH WATER TO FORM TRIAZOLINONE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5475115-A | Reacting sulfonyltriazole with alkali hydroxide followed by acidification | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0661277-A1 | Process for making triazolines and new untermediates used therein | BAYER AG (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0657437-A1 | Process and novel intermediates for the preparation of triazolinones | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |