Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 12/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15250522 | 0.95 | ACACB (0.49) | ACACBAPPDRD2DRD4DRD3 | |
| SCHEMBL15250538 | 0.95 | ACACB (0.49) | ACACBAPPDRD2DRD4DRD3 | |
| SCHEMBL15250551 | 0.91 | ACACB (0.46) | ACACBAPPMEN1KMT2ACHRNB2 | |
| SCHEMBL15250552 | 0.91 | ACACB (0.46) | ACACBAPPMEN1KMT2ACHRNB2 | |
| SCHEMBL82225 | 0.91 | DRD2 (0.52) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL15138934 | 0.89 | DRD2 (0.50) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL20372704 | 0.89 | DRD2 (0.50) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL20872263 | 0.89 | DRD2 (0.50) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL9512229 | 0.88 | APP (0.51) | ACACBAPPDRD2DRD4DRD3 | |
| SCHEMBL15250576 | 0.86 | MCHR1 (0.56) | ACACBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |