SCHEMBL9510157

SCHEMBL9510157

CCCCC[C@H]1CC[C@H](c2ccc(C#Cc3ccc(OCCCC)c(F)c3F)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.34
CYP2C9 P11712 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
SPHK1 Q9NYA1 2/20 0.32
S1PR3 Q99500 1/20 0.32
ACACB O00763 3/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
PPARG P37231 2/20 0.31
PPARA Q07869 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509024 0.99 RAB9A (0.34) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9511345 0.99 RAB9A (0.34) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9511356 0.98 CYP2C9 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9508734 0.97 ACACB (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9512396 0.97 SPHK1 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9508780 0.97 SPHK1 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9512502 0.97 RAB9A (0.35) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9512361 0.96 SPHK1 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9511489 0.96 SPHK1 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A
SCHEMBL9511457 0.96 CYP2C9 (0.33) RAB9ACYP2C9HRH3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308438-B1 LIQUID CRYSTAL PHASE CONTAINING TOLANES MERCK PATENT GmbH (DE) 1993-09-29 EP disclosed