Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739519 | 0.85 | TNKS (0.71) | TNKSMAOBNPC1RAB9AMAPT | |
| SCHEMBL980266 | 0.85 | TNKS (0.56) | TNKSMAOBFFAR1NPC1RAB9A | |
| SCHEMBL5787047 | 0.82 | TP53 (0.55) | TNKSMAOBNPC1RAB9AMAPT | |
| SCHEMBL977340 | 0.80 | FFAR1 (0.58) | TNKSMAOBFFAR1HDAC6 | |
| SCHEMBL11247199 | 0.79 | FFAR1 (0.57) | TNKSMAOBFFAR1NPC1RAB9A | |
| SCHEMBL8169813 | 0.79 | HSD17B10 (0.52) | MAOBFFAR1NPC1RAB9AMAPT | |
| SCHEMBL2342209 | 0.78 | MAOA (0.53) | MAOBNPC1RAB9AMAPTMEN1 | |
| SCHEMBL6485304 | 0.77 | TNKS (0.57) | TNKSNPC1RAB9AMAPTMEN1 | |
| SCHEMBL1390990 | 0.77 | HSD17B10 (0.55) | MAOBNPC1RAB9AMAPTMEN1 | |
| SCHEMBL11243729 | 0.76 | FFAR1 (0.55) | TNKSMAOBFFAR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229363-B1 | Ultraviolet radiation stabilized polyphenylene ether resins | GEN ELECTRIC (US) | 1993-10-20 | — | — | EP | claimed |
| EP-0229363-A2 | Ultraviolet radiation stabilized polyphenylene ether resins | GENERAL ELECTRIC COMPANY (US) | 1987-07-22 | — | — | EP | claimed |
| US-4665112-A | BENZOFURAN DERIVATIVE, DISCOLORATION INHIBITION | GENERAL ELECTRIC COMPANY (US) | 1987-05-12 | — | — | US | claimed |