Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493123 | 0.94 | MAOB (0.52) | TDP1MAOBMAOAACHEBCHE | |
| Hydrochloric Acid SCHEMBL9510294 | 0.93 | MAOB (0.51) | TDP1MAOBMAOAACHEBCHE | |
| SCHEMBL9157478 | 0.84 | TDP1 (0.44) | TDP1MAOBMAOAACHECPT1B | |
| SCHEMBL9510623 | 0.78 | HTR7 (0.54) | POLBHTR7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9314272 | 0.78 | MAOB (0.47) | MAOBMAOAACHEBCHEPOLB | |
| Hydrochloric Acid SCHEMBL9511571 | 0.78 | HTR7 (0.53) | POLBHTR7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6786556 | 0.77 | MEN1 (0.67) | MAOBMAOAACHEBCHEMEN1 | |
| SCHEMBL9510247 | 0.77 | SMN1; SMN2 (0.50) | POLBHTR7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9314268 | 0.77 | MAOB (0.46) | MAOBMAOAACHEBCHEPOLB | |
| SCHEMBL9488480 | 0.77 | MAOB (0.46) | MAOBMAOAACHEBCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372410-B1 | Use of heterocyclic amides to inhibit tumor metastasis | SEARLE & CO (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0190685-B1 | HETEROCYCLIC AMIDES | G.D. Searle & Co. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5010080-A | !anticarcinogenic agents | G. D. SEARLE & CO. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4981853-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | G. D. SEARLE & CO. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4959364-A | Method of treating inflammation, allergy, asthma and proliferative skin disease using heterocyclic amides | G. D. SEARLE & CO. (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0372410-A2 | Use of heterocyclic amides to inhibit tumor metastasis | G.D. Searle & Co. (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0190685-A2 | Heterocyclic amides | G.D. Searle & Co. (US) | 1986-08-13 | — | — | EP | disclosed |