Styrene

Styrene

SCHEMBL9510293

C=C(C)C(=O)OC.C=C(CC)C(=O)OCCCCCC.C=C(O)C(=O)OCC.C=Cc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
POLB P06746 2/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
LMNA P02545 4/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.36
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
MAPT P10636 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PLIN1 O60240 1/20 0.34
PLIN5 Q00G26 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4146543 0.94 TSHR (0.50) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL7634818 0.92 TSHR (0.48) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL10884189 0.90 TSHR (0.56) TSHRSMN1; SMN2NPC1RAB9AMEN1
Styrene SCHEMBL7210426 0.88 TSHR (0.44) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL11208181 0.88 TSHR (0.56) TSHRSMN1; SMN2NPC1RAB9ATDP1
SCHEMBL6048367 0.87 TSHR (0.57) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL7674295 0.87 TSHR (0.45) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL27531091 0.86 TSHR (0.57) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL491216 0.86 TSHR (0.48) TSHRSMN1; SMN2NPC1RAB9ATDP1
Styrene SCHEMBL6449703 0.86 MEN1 (0.42) TSHRSMN1; SMN2MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315702-B1 THERMOSETTING WATER PAINT COMPOSITION NIPPON PAINT CO., LTD. (JP) 1993-10-06 EP disclosed
EP-0315702-A1 THERMOSETTING WATER PAINT COMPOSITION NIPPON PAINT CO., LTD. (JP) 1989-05-17 EP disclosed