Styrene

Styrene

SCHEMBL6449703

C=C(C)C(=O)OC.C=C(CCCCCC)C(=O)OCC.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.38
ADORA3 P0DMS8 1/20 0.37
FAAH O00519 2/20 0.37
EGFR P00533 1/20 0.37
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1476489 0.92 MEN1 (0.49) MEN1KMT2AALDH1A1MAPTLMNA
Styrene SCHEMBL28077574 0.88 TDP1 (0.46) MEN1KMT2AALDH1A1LMNATDP1
Styrene SCHEMBL2942058 0.87 LMNA (0.44) MEN1KMT2AALDH1A1LMNATDP1
Styrene SCHEMBL2134956 0.86 LMNA (0.39) MEN1KMT2AALDH1A1LMNAKDM4E
Styrene SCHEMBL10489430 0.86 MEN1 (0.53) MEN1KMT2AALDH1A1MAPTLMNA
Styrene SCHEMBL9510293 0.86 TSHR (0.44) MEN1KMT2AALDH1A1MAPTLMNA
Styrene SCHEMBL4146543 0.84 TSHR (0.50) ALDH1A1MAPTLMNAKDM4ECYP3A4
Styrene SCHEMBL28688942 0.83 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTLMNA
Styrene SCHEMBL8861021 0.83 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTLMNA
Styrene SCHEMBL9843195 0.83 LMNA (0.36) MEN1KMT2AALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861474-B2 Golf ball layers and method of manufacture TAYLOR MADE GOLF COMPANY, INC. (US) 2005-03-01 US claimed
US-20030130052-A1 Golf ball layers and method of manufacture TAYLOR MADE GOLF COMPANY, INC. 2003-07-10 US claimed
US-6861474-B2 Golf ball layers and method of manufacture TAYLOR MADE GOLF COMPANY, INC. (US) 2005-03-01 US disclosed
US-20030130052-A1 Golf ball layers and method of manufacture TAYLOR MADE GOLF COMPANY, INC. 2003-07-10 US disclosed