Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 4/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510271 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29531361 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL30913906 | 0.91 | ALDH1A1 (0.43) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL1711472 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29629477 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL1711477 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL8645853 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL2544247 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL15443060 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29538996 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LAP3MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280474-B1 | Macromolecular platinum antitumor compounds | JOHNSON MATTHEY INC (US) | 1993-11-03 | — | — | EP | disclosed |
| US-4793986-A | POLYSACCHARIDE CARRIER, ACTIVATED, LINKED TO PLATINUM COMPOUND THROUGH AMINE-CONTAINING LIGAND | JOHNSON MATTHEY, INC. (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0280474-A2 | Macromolecular platinum antitumor compounds | JOHNSON MATTHEY, INC., (US) | 1988-08-31 | — | — | EP | disclosed |