Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CPS1 | P31327 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677716 | 0.81 | KDM1A (0.44) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL29447917 | 0.79 | TAAR1 (0.44) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL8132364 | 0.79 | POLB (0.46) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL8165383 | 0.78 | HSD17B10 (0.45) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL2425644 | 0.77 | TAAR1 (0.50) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL7670936 | 0.77 | POLB (0.45) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL3321047 | 0.77 | KDM1A (0.44) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL3851963 | 0.77 | IDO1 (0.47) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL2290549 | 0.77 | KDM4E (0.46) | KDM1AMAOAMAOBAPLNRCYP1A1 | |
| SCHEMBL489792 | 0.77 | ALDH1A1 (0.47) | KDM1AMAOAMAOBAPLNRCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272115-B1 | OPTICALLY ACTIVE LIQUID CRYSTALLINE BIPHENYL COMPOUND | Chisso Corporation (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0272115-A2 | Optically active liquid crystalline biphenyl compound | Chisso Corporation (JP) | 1988-06-22 | — | — | EP | disclosed |