Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | IDH1 | O75874 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765334 | 0.90 | GAA (0.55) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL9512076 | 0.87 | TBXA2R (0.55) | GAAPOLBSMN1; SMN2TSHRIDH1 | |
| SCHEMBL28499595 | 0.80 | KDM4E (0.56) | GAANPSR1POLBSMN1; SMN2ATM | |
| SCHEMBL11364586 | 0.80 | KMT2A (0.69) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL11363199 | 0.78 | TSHR (0.75) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL27288747 | 0.76 | GAA (0.55) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL11379516 | 0.76 | TBXA2R (0.74) | GAANPSR1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7924006 | 0.75 | SMN1; SMN2 (0.61) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL9765332 | 0.75 | SMN1; SMN2 (0.58) | GAANPSR1POLBSMN1; SMN2TSHR | |
| SCHEMBL9510518 | 0.75 | SMN1; SMN2 (0.58) | GAANPSR1POLBSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0325245-A1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |