Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510518 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9777951 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9512747 | 0.84 | HSP90AA1 (0.55) | TSHRPOLBHSP90AA1HSP90AB1PDK1 | |
| SCHEMBL11363199 | 0.82 | TSHR (0.75) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL11364586 | 0.82 | KMT2A (0.69) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL10339107 | 0.82 | PKM (0.51) | SMN1; SMN2TSHRGAAPOLBALDH1A1 | |
| SCHEMBL8440203 | 0.81 | TSHR (0.52) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL11379516 | 0.81 | TBXA2R (0.74) | SMN1; SMN2TSHRGAANPSR1ALDH1A1 | |
| SCHEMBL10701921 | 0.80 | ALDH1A1 (0.56) | TSHRPOLBHSP90AA1HSP90AB1PDK1 | |
| SCHEMBL7924006 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRGAANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |