Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.59 |
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.59 |
| ▸ | STS | P08842 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13374338 | 1.00 | HSD17B1 (0.59) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL4893106 | 0.90 | STS (0.69) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL4893115 | 0.90 | STS (0.69) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL220159 | 0.88 | ESR1 (0.63) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL18652154 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL218464 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL218463 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL2738481 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL217082 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA | |
| SCHEMBL217081 | 0.88 | STS (0.62) | HSD17B1ESR1ESR2STSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316320-B1 | REDUCTION OF REPRODUCTIVE LOSSES | COMMW SCIENT IND RES ORG (AU) | 1993-11-03 | — | — | EP | disclosed |
| EP-0316320-A4 | REDUCTION OF REPRODUCTIVE LOSSES. | COMMW SCIENT IND RES ORG (AU) | 1989-12-04 | — | — | EP | disclosed |
| EP-0316320-A1 | REDUCTION OF REPRODUCTIVE LOSSES. | COMMW SCIENT IND RES ORG (AU) | 1989-05-24 | — | — | EP | disclosed |
| WO-1988000470-A1 | REDUCTION OF REPRODUCTIVE LOSSES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 1988-01-28 | — | — | WO | disclosed |
| US-4457914-A | VACCINATING AGAINST ANDROGEN OR ESTROGEN | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1984-07-03 | — | — | US | disclosed |
| US-4331657-A | IMMUNIZING AGAINST A STEROIDAL ANDROGEN OR OESTROGEN | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1982-05-25 | — | — | US | disclosed |