Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911503 | 0.93 | ATM (0.48) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL4138556 | 0.89 | DRD2 (0.46) | ATMMAPTALDH1A1ARDRD2 | |
| SCHEMBL11015073 | 0.84 | MAPT (0.44) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10911472 | 0.84 | ATM (0.53) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL8529890 | 0.81 | DRD2 (0.46) | ATMMAPTALDH1A1ARDRD2 | |
| SCHEMBL30888660 | 0.78 | HTR2A (0.41) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL4779518 | 0.78 | HTR2A (0.41) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL17785691 | 0.78 | MAPT (0.42) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10909719 | 0.78 | ATM (0.48) | ATMKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL30888682 | 0.74 | KDM4E (0.41) | ATMKDM4EMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292885-B1 | CATALYTIC TRANSFER-HYDROGENATION WITH AROMATIC NITRO COMPOUNDS AS HYDROGEN ACCEPTOR | BASF Aktiengesellschaft (DE) | 1993-09-08 | — | — | EP | disclosed |
| EP-0292885-A2 | Catalytic transfer-hydrogenation with aromatic nitro compounds as hydrogen acceptor | BASF Aktiengesellschaft (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0173208-A1 | Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-05 | — | — | EP | disclosed |