Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510974 | 0.96 | NAAA (0.44) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9508174 | 0.95 | NAAA (0.47) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9511994 | 0.95 | NAAA (0.47) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9512029 | 0.95 | NAAA (0.47) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9510983 | 0.95 | NAAA (0.47) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9511931 | 0.87 | NAAA (0.38) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL9509807 | 0.85 | MEN1 (0.44) | CES2CES1ALDH1A1CYP3A4NPSR1 | |
| SCHEMBL9510951 | 0.84 | MEN1 (0.50) | CES2CES1FAAHATM | |
| SCHEMBL9509762 | 0.82 | MEN1 (0.53) | CES2CES1FAAHATM | |
| SCHEMBL9508242 | 0.82 | MEN1 (0.53) | CES2CES1FAAHATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350334-B1 | A process for producing fluorine-containing compounds | NIPPON MINING CO (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-5126482-A | Process for producing fluorine-containing carboxylic acids | NIPPON MINING CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0350334-A2 | A process for producing fluorine-containing compounds | NIKKO KYODO CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |