Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509826 | 1.00 | TDP1 (0.39) | TDP1HSD17B10EPHX2TSHRSPHK1 | |
| SCHEMBL9511106 | 1.00 | TDP1 (0.39) | TDP1HSD17B10EPHX2TSHRSPHK1 | |
| SCHEMBL9507530 | 0.94 | DNM1 (0.39) | TDP1HSD17B10EPHX2SPHK1MAPT | |
| SCHEMBL9509848 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9509804 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9509821 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9507424 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9508720 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9511188 | 0.92 | DNM1 (0.42) | TDP1EPHX2SPHK1MAPTDNM1 | |
| SCHEMBL9508008 | 0.86 | TDP1 (0.47) | TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |