⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21633843 | 0.92 | IDO1 (0.46) | — | |
| SCHEMBL5358862 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL7434377 | 0.79 | CYP1A2 (0.59) | — | |
| SCHEMBL28113850 | 0.78 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL7547399 | 0.77 | CYP1A2 (0.56) | — | |
| SCHEMBL1805218 | 0.77 | CYP1A2 (0.56) | — | |
| SCHEMBL283304 | 0.75 | TP53 (0.50) | — | |
| SCHEMBL687371 | 0.75 | — | — | |
| SCHEMBL143961 | 0.73 | CYP1A2 (0.68) | — | |
| SCHEMBL1149394 | 0.73 | IDO1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3610 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444480-B | Preparation method of high-performance aromatic polyester capable of being chemically recycled | 四川大学 | 2024-04-26 | — | — | CN | claimed |
| CN-115872939-A | 2,3-dihydroquinazoline-4 (1H) -ketone derivative and preparation and application thereof | 武汉科技大学 | 2023-03-31 | — | — | CN | claimed |
| CN-113121524-A | Heterocyclic sulfoximine compound and intermediate, preparation method and application thereof | 南京创济生物医药有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-107629020-B | 4H-1,2, 4-oxadiazine-5 (6H) -ketone compound and synthetic method thereof | 湖北科技学院 | 2020-09-04 | — | — | CN | claimed |
| CN-107176925-B | Synthesis method of polysubstituted imidazoline-2, 4-diketone compound | 湖北科技学院 | 2020-04-28 | — | — | CN | claimed |
| EP-3160977-A2 | BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS | The University of Kansas (US) | 2017-05-03 | — | — | EP | claimed |
| CN-106459278-A | Improved catalyst system for the preparation of polyethylene copolymers in a high temperature solution polymerization process | 博里利斯股份公司 | 2017-02-22 | — | — | CN | claimed |
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | claimed |
| EP-3102034-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC Foundation For Research Development (US) | 2016-12-14 | — | — | EP | claimed |
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | claimed |
| WO-1990014235-A1 | HEAT-SENSITIVE RECORD MATERIAL | SMITH & MCLAURIN LIMITED (GB) | 1990-11-29 | — | — | WO | claimed |
| US-4742073-A | ANTIGLAUCOMA | BUNDGAARD HANS (DK) | 1988-05-03 | — | — | US | claimed |
| EP-0229034-A2 | Hexopyranoses and compositions for agricultural use | HER MAJESTY THE QUEEN in right of New Zealand Department of Scientific and Industrial Research (NZ) | 1987-07-15 | — | — | EP | claimed |
| US-4614819-A | REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-30 | — | — | US | claimed |
| US-4604460-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1986-08-05 | — | — | US | claimed |
| US-4478997-A | 1-Oxadethiacepham compounds | SHIONOGI & CO., LTD. (JP) | 1984-10-23 | — | — | US | claimed |
| EP-0106541-A2 | Pilocarpine prodrugs | Bundgaard, Hans (DK) | 1984-04-25 | — | — | EP | claimed |
| US-4443598-A | ANTIBIOTICS AND INTERMEDIATES | SHIONOGI & CO., LTD. (JP) | 1984-04-17 | — | — | US | claimed |
| US-4148625-A | Tetrahydroisophthalimide compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-10 | — | — | US | claimed |
| US-3941799-A | 6-Substituted-11b-phenyl-3, 11bH-oxazirino[2,3-d]-s-triazol[4,3-a][1,4]benzodiazepines | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | claimed |