Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979925 | 0.98 | SPHK1 (0.42) | SPHK1DNM1EPHX2FAAHLPAR1 | |
| SCHEMBL9508665 | 0.98 | SPHK1 (0.42) | SPHK1DNM1EPHX2FAAHLPAR1 | |
| SCHEMBL9508761 | 0.98 | SPHK1 (0.42) | SPHK1DNM1EPHX2FAAHLPAR1 | |
| SCHEMBL9508060 | 0.96 | DNM1 (0.38) | SPHK1DNM1EPHX2TDP1LPAR1 | |
| SCHEMBL9507530 | 0.90 | DNM1 (0.39) | SPHK1DNM1EPHX2FAAHTDP1 | |
| SCHEMBL14380991 | 0.89 | DNM1 (0.45) | SPHK1DNM1EPHX2FAAHOPRM1 | |
| SCHEMBL9507424 | 0.88 | DNM1 (0.42) | SPHK1DNM1EPHX2FAAHTDP1 | |
| SCHEMBL9511188 | 0.88 | DNM1 (0.42) | SPHK1DNM1EPHX2FAAHTDP1 | |
| SCHEMBL9508720 | 0.88 | DNM1 (0.42) | SPHK1DNM1EPHX2FAAHTDP1 | |
| SCHEMBL9509848 | 0.88 | DNM1 (0.42) | SPHK1DNM1EPHX2FAAHTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |