SCHEMBL9511191

SCHEMBL9511191

Clc1c(Cl)c(Cl)c2c(c1Cl)Sc1c(Cl)c(Cl)c(Cl)c(Cl)c1S2

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589135 0.80
SCHEMBL11588866 0.80
SCHEMBL11431827 0.78
SCHEMBL9507655 0.73 AHR (0.56)
SCHEMBL11590927 0.72
SCHEMBL11707798 0.72 CYP3A4 (0.46) ALDH1A1HPGDTSHRHSD17B10
SCHEMBL11711164 0.71 CYP3A4 (0.31)
Perchlorobenzene SCHEMBL26562 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL1330781 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL8872243 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed
US-4031147-A CATALYST HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-06-21 US disclosed
US-4024198-A Process for the chlorination of toluene HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-05-17 US disclosed