Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578004 | 0.86 | ALDH1A1 (0.62) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL16366695 | 0.86 | ALDH1A1 (0.62) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6546118 | 0.85 | ALDH1A1 (0.69) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1784136 | 0.84 | TSHR (0.57) | TSHRALDH1A1LMNAPDCD1CD274 | |
| SCHEMBL1142463 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12083567 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1142467 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2362569 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27262020 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26775029 | 0.84 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |