Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544579 | 0.79 | MAPT (0.49) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL12463067 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL22226380 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL22205032 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL22205033 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL22226190 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL5521516 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTMEN1KMT2ACA2 | |
| SCHEMBL12874129 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2LMNACYP3A4MAPT | |
| SCHEMBL2112085 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTMEN1KMT2ACA2 | |
| SCHEMBL13798670 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022829-C | Synthesis of beta-lactams with metal compounds | UNIV UTRECHT (NL) | 1993-11-24 | — | — | CN | disclosed |
| EP-0281177-B1 | A SYNTHESIS FOR BETA-LACTAMS WITH THE AID OF A METAL COMPOUND | RIJKSUNIVERSITEIT UTRECHT (NL) | 1993-09-01 | — | — | EP | disclosed |
| US-4898955-A | INTERMEDIATE FOR PREPARING TRANS-B-LACTAMS | GIST-BROCADES N.V. (NL) | 1990-02-06 | — | — | US | disclosed |
| EP-0281177-A1 | A synthesis for beta-lactams with the aid of a metal compound | RIJKSUNIVERSITEIT UTRECHT (NL) | 1988-09-07 | — | — | EP | disclosed |
| CN-88100703-A | Synthesis of beta-lactams with metal compounds | — | 1988-08-17 | — | — | CN | disclosed |