Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 6/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512324 | 1.00 | FFAR1 (0.40) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9512364 | 0.96 | TSHR (0.45) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9508912 | 0.96 | TSHR (0.45) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9510003 | 0.95 | TSHR (0.43) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9508736 | 0.92 | HSD17B10 (0.48) | TSHRHSD17B10MPLHSD11B1RARB | |
| SCHEMBL9508728 | 0.92 | HSD17B10 (0.48) | TSHRHSD17B10MPLHSD11B1RARB | |
| SCHEMBL9510034 | 0.92 | TSHR (0.41) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9508790 | 0.92 | TSHR (0.41) | FFAR1TSHRHSD17B10MPLHSD11B1 | |
| SCHEMBL9512412 | 0.92 | FFAR1 (0.41) | FFAR1MPL | |
| SCHEMBL9512352 | 0.92 | FFAR1 (0.41) | FFAR1MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |