Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512364 | 1.00 | TSHR (0.45) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL9512324 | 0.96 | FFAR1 (0.40) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL9511284 | 0.96 | FFAR1 (0.40) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL9512420 | 0.95 | HSD17B10 (0.49) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508728 | 0.94 | HSD17B10 (0.48) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL9508736 | 0.94 | HSD17B10 (0.48) | TSHRHSD17B10RARBHSD11B1RARA | |
| SCHEMBL10512751 | 0.93 | TSHR (0.40) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL10511580 | 0.93 | TSHR (0.40) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL10511143 | 0.93 | TSHR (0.40) | TSHRHSD17B10RARBNPC1RAB9A | |
| SCHEMBL10519630 | 0.93 | TSHR (0.40) | TSHRHSD17B10RARBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |