Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510811 | 0.94 | AGXT (0.45) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL9510780 | 0.94 | AGXT (0.45) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL6214405 | 0.85 | LOXL2 (0.56) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL4048647 | 0.78 | LOXL2 (0.60) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL5542824 | 0.77 | AGXT (0.45) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL2088773 | 0.75 | LOXL2 (0.53) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL8688187 | 0.75 | MAPT (0.63) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL7796043 | 0.75 | LOXL2 (0.62) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL19813189 | 0.75 | MAPT (0.63) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL11243675 | 0.75 | MAPT (0.63) | AGXTLOXL2SMN1; SMN2L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-B1 | ETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-22 | — | — | EP | disclosed |
| US-5039697-A | Adrenergic stimulants, bronchodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5032609-A | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| US-5002966-A | Adrenergic Stimulants | GLAXO GROUP LIMITED (GB) | 1991-03-26 | — | — | US | disclosed |
| EP-0322164-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |