SCHEMBL9511329

SCHEMBL9511329

Fc1ccc2c(c1)Sc1cc(F)ccc1O2

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 0.42
HTR2C P28335 1/20 0.32
AHR P35869 2/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
FABP6 P51161 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PDE3A Q14432 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661624 1.00 NOX1 (0.42) NOX1HTR2CAHRCA3CA6
SCHEMBL38661040 0.81 NOX1 (0.38) NOX1HTR2CCA3CA6CA5A
SCHEMBL11828411 0.78 CTNNB1 (0.35)
SCHEMBL11827566 0.78 ABCB11 (0.37)
SCHEMBL8208500 0.77 NOX1 (0.44) NOX1HTR2CAHRCYP1A2CYP2A6
SCHEMBL11822353 0.76 PTGS1 (0.48) HTR2CCYP1A2MAPT
SCHEMBL15362856 0.74
SCHEMBL29411773 0.74 NOX1 (0.48) NOX1CA3CA6CA5ACA9
SCHEMBL9508923 0.74 NOX1 (0.48) NOX1CA3CA6CA5ACA9
SCHEMBL9511403 0.74 NOX1 (0.48) NOX1CA3CA6CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed